Erratum: corrigendum: MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation
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چکیده
منابع مشابه
Extracellular Proteins Needed for C. elegans Mechanosensation
The mec-5 and mec-9 genes encode putative extracellular proteins that allow a set of six touch receptor neurons in C. elegans to respond to gentle touch. MEC-5 is a collagen made by the epidermal cells that surround the touch cells. Mutations causing touch insensitivity affect the Gly-X-Y repeats of this collagen. mec-9 produces two transcripts, the larger of which is expressed in the touch cel...
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In Caenorhabditis elegans, gentle touch is sensed by the anterior (ALM and AVM) and posterior (PLM) touch receptor neurons. Anterior, but not posterior, touch is affected by several stress conditions via the action of AKT kinases and the DAF-16/FOXO transcription factor. Here we show that a ubiquitination-dependent mechanism mediates such effects. AKT-1/AKT kinase and DAF-16 alter the transcrip...
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Temporal processing and context dependency in C. elegans mechanosensation Mochi Liu1, Anuj K Sharma2, Joshua W Shaevitz1,2, Andrew M Leifer2,3* *For correspondence: [email protected] (AML) 1Lewis-Sigler Institute for Integrative Genomics, Princeton University, USA; 2Department of Physics, Princeton University, Princeton University, USA; 3Princeton Neuroscience Institute, Princeton University...
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Previous work has shown that C. elegans MEC-8 is a putative RNA-binding protein that promotes specific alternative splices of unc-52 transcripts. unc-52 encodes homologs of mammalian perlecan that are located extracellularly between muscle and hypodermis and are essential for muscle development in both embryos and larvae. We show that MEC-8 is a nuclear protein found in hypodermis at most stage...
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ژورنال
عنوان ژورنال: Nature
سال: 2002
ISSN: 0028-0836,1476-4687
DOI: 10.1038/nature00853